InquiryThe nervous system is the system that plays a dominant role in the regulation of physiological functions in the body and is mainly composed of nerve cells (neurons) and glia. The nervous system plays a leading role in maintaining the homeostasis of the body's internal environment, maintaining the integrity and unity of the body and its coordination and balance with the external environment. Mature brain tissue in animals or humans is more delicate compared to other tissues and nerve cells are fragile; brain cells die in large numbers 6-10 minutes after brain tissue is removed from the body.
How we use spatial-omics approaches to explain the complexity of the nervous system
CD Genomics provides single-cell analysis and spatial gene expression solutions for neuroscientists. Provides an extremely valuable data resource for understanding the degree of heterogeneity in neural cell development and the cellular characteristics associated with neuro brain tissue from multiple perspectives. Enables our clients to gain a comprehensive understanding of neuronal cell types, development, and gene activity profiles of the human brain, such as neurons and glial cells.
What we can do for our clients
- Build a full picture of the complex biology of neurological diseases from multiple dimensions.
- Discover the molecular basis of mental disorders and characterize cellular phenotypes associated with the disease.
- Dissect the molecular pathways that control neural cell differentiation and reveal the dynamics of the regulatory landscape during the process.
- Analyze the laminar organization of the cerebral cortex and reveal the structural and functional relationships of the cerebral cortex.
- Examine disease-related gene expression profiles in different brain regions under normal and disease.
- Understand neural development and differentiation.
- Identify novel cellular subtype markers.
Research directions that can be applied in practice
- Response of astrocytes to inflammatory injury.
- Understand the cellular and molecular mechanisms behind the normal function and neurological disease states.
- Regulation of expression of specific cell type genes and its impact on Alzheimer's disease.
- Changes in the brain neurogenesis microenvironment with age and the factors influencing it.
- Exploring the temporal patterns of neuropathic pain after nerve injury.
We do it better
CD Genomics provides spatial-omics-based solutions for clients in the field of neuroscience. Cell populations such as neurons, astrocytes, oligodendrocytes, and microglia and their interrelationships can be analyzed to deepen our clients' understanding of neural cell identification and molecular insights into disease states. It also provides more accurate data for the study of various neurological-related diseases.
