InquirySome cells are found in small but important amounts in blood and tissues, such as stem cells, circulating endothelial cells, circulating tumor cells, and residual diseased cells. Accurate detection and analysis of these rare cells is key to understanding disease processes and developmental mechanisms.
How we detect rare cells
CD Genomics' single-cell multi-omics-based technology (including multiple scRNA-seq methods and analysis algorithms) provides a comprehensive and flexible platform for rare cell analysis from sample collection and rare cell identification to a single cell or tissue micro-region retrieval, and the high sensitivity and specificity of the methods we offer enable the application of rare cells.
CD Genomics' multi-parametric imaging and analysis platform enable highly sensitive identification detection, isolation, and characterization of rare cells, allowing researchers to extend disease treatment by monitoring rare cells of interest, enabling deep phenotyping and flexible biomarker analysis through multiple imaging channels.
General analysis flow
- Single-cell or histology slides are prepared from blood or fixed tissue samples.
- Single cells from blood or isolated fresh tissue are barcoded and stained for live/dead, surface, and/or intracellular markers.
- Collection of tissue on histology slides is performed.
- The de-barcoded data is loaded into the chosen bioinformatics analysis platform for data analysis.
In addition, CD Genomics offers a platform that is not limited by sample type, with workflows that can accommodate fixed or live-cell samples, and we can provide researchers with methods to study new rare cell populations and their signature genes in vitro, based on their role in health and disease, after identifying them.
Practical applications of rare cell testing services
- Inferring the interactions of cell types.
- Mapping the types that make up the tumor microenvironment.
- Assess the presence and identity of tumor-infiltrating immune cells in cancer.
- Examine cellular phenotypes, immune effector functions, and even dynamic changes.
- Determine the enrichment of cell types within regions of interest in tissues.
- Analyze the spatial co-localization patterns of cells.
Why choose us
No sacrifice in throughput or accuracy. We support the simultaneous detection of multiple cellular parameters and guarantee high precision analysis at very high sample throughput.
No sacrifice in the speed of detection. With the ability to collect up to 20 million cells in a single pass, the high sample acquisition rate and sample size help researchers detect rare cells quickly and accurately without compromising the quality of the data.
No sacrifice of precious samples. We support no-elution, no-cleavage protocols to maximize the retention of valuable samples, avoid unnecessary cell loss, and simplify sample preparation steps.
